Sound Waves Shake Pharmaceuticals into Cocrystals

Jerry Salan and David J. am Ende, “Sound Waves Shake Pharmaceuticals into Cocrystals”, Chemical & Engineering News, February 6, 2014.



Chemical Engineering: Resonant acoustic mixing provides a green, scalable way to cocrystallize compounds


Ideally, the active ingredient of an oral medication should readily form crystals, dissolve quickly in the digestive tract, and be rapidly absorbed in the body. If a compound can’t do those things on its own, scientists can help it by crystallizing the compound with one or more other compounds, forming cocrystals with the desired properties.


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